Effect of Genetic Modifications on Physical and Functional Titers of Adenoviral Cancer Gene Therapy Constructs-Reference-Cited by-同舟云学术

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Effect of Genetic Modifications on Physical and Functional Titers of Adenoviral Cancer Gene Therapy Constructs

Published:2019-06 Issue:6 Volume:30 Page:740-752
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Heiniö Camilla¹,Sorsa Suvi¹²,Siurala Mikko¹²,Grönberg-Vähä-Koskela Susanna¹,Havunen Riikka¹²,Haavisto Elina²,Koski Anniina¹,Hemminki Otto¹³,Zafar Sadia¹,Cervera-Carrascon Víctor¹²,Munaro Eleonora¹,Kanerva Anna¹⁴,Hemminki Akseli¹²⁵

Affiliation:

1. Cancer Gene Therapy Group, Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.

2. TILT Biotherapeutics Ltd., Helsinki, Finland.

3. Department of Urology, Helsinki University Hospital, Helsinki, Finland.

4. Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland.

5. Comprehensive Cancer Center, Helsinki University Hospital, Helsinki, Finland.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/hum.2018.240

Reference51 articles.

1. Adenoviruses as gene/vaccine delivery vectors: promises and pitfalls

2. Gene therapy clinical trials worldwide to 2017: An update

3. A Phase 1 Trial of Oncolytic Adenovirus ICOVIR-5 Administered Intravenously to Cutaneous and Uveal Melanoma Patients

4. Biodistribution Analysis of Oncolytic Adenoviruses in Patient Autopsy Samples Reveals Vascular Transduction of Noninjected Tumors and Tissues

5. Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection

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1. A Single Dose of a Hybrid hAdV5-Based Anti-COVID-19 Vaccine Induces a Long-Lasting Immune Response and Broad Coverage against VOC;Vaccines;2021-09-29

2. Adenovirus Armed With TNFa and IL2 Added to aPD-1 Regimen Mediates Antitumor Efficacy in Tumors Refractory to aPD-1;Frontiers in Immunology;2021-07-23

3. TNFa and IL2 Encoding Oncolytic Adenovirus Activates Pathogen and Danger-Associated Immunological Signaling;Cells;2020-03-26

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