Effects of Thyroid Function on Hemostasis, Coagulation, and Fibrinolysis: A Mendelian Randomization Study

Author:

Ellervik Christina1234ORCID,Mora Samia56,Kuś Aleksander789ORCID,Åsvold Bjørn1011ORCID,Marouli Eirini12,Deloukas Panos1213,Sterenborg Rosalie B.T.M.7814,Teumer Alexander1516ORCID,Burgess Stephen1718,Sabater-Lleal Maria1920,Huffman Jennifer21,Johnson Andrew D.22,Trégouet David-Alexandre23,Smith Nicolas L.242526,Medici Marco7814,DeVries Paul S.27,Chasman Daniel I.282930,Kjaergaard Alisa D.31ORCID

Affiliation:

1. Department of Laboratory Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.

2. Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.

3. Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

4. Department of Data and Data Support, Region Zealand, Sorø, Denmark.

5. Center for Lipid Metabolomics, Division of Preventive Medicine; Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

6. Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

7. Department of Internal Medicine, Academic Center for Thyroid Diseases; Erasmus Medical Center, Rotterdam, The Netherlands.

8. Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.

9. Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland.

10. K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.

11. Department of Endocrinology, Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.

12. William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

13. Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.

14. Department of Internal Medicine, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

15. Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.

16. DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany.

17. MRC Biostatistics Unit, University of Cambridge, Cambridge, United Kingdom.

18. Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.

19. Genomics of Complex Diseases Group, Research Institute Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, Barcelona, Spain.

20. Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.

21. Scientific Director for Genomics Research, Center for Population Genomics, Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC), VA Boston Healthcare System, Boston, Massachusetts, USA.

22. National Heart, Lung and Blood Institute's The Framingham Heart Study, Population Sciences Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, Framingham, Massachusetts, USA.

23. INSERM U1219, Bordeaux Population Health Research Center, University of Bordeaux, Bordeaux, France.

24. Department of Epidemiology, University of Washington, Seattle, Washington, USA.

25. Kaiser Permamente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, Washington, USA.

26. Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, Seattle, Washington, USA.

27. Department of Epidemiology, Human Genetics, and Environmental Sciences, Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

28. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

29. Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

30. Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

31. Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.

Publisher

Mary Ann Liebert Inc

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

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