Lysosomal Proteolysis Is the Primary Degradation Pathway for Cytosolic Ferritin and Cytosolic Ferritin Degradation Is Necessary for Iron Exit

Author:

Zhang Yinghui123,Mikhael Marc4,Xu Dongxue15,Li Yiye1,Soe-Lin Shan4,Ning Bo1,Li Wei6,Nie Guangjun1,Zhao Yuliang16,Ponka Prem4

Affiliation:

1. CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing, China.

2. Graduate University of Chinese Academy of Sciences, Beijing, China.

3. Key Laboratory for High Altitude Environment and Disease-Related Genes, Department of Medicine, Tibet Nationalities Institute, Xianyang, Shanxi, China.

4. Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

5. Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, Jilin University, Changchun, China.

6. Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

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