Redox-Dependent Modulation of T-Type Ca2+ Channels in Sensory Neurons Contributes to Acute Anti-Nociceptive Effect of Substance P-Reference-Cited by-同舟云学术

Redox-Dependent Modulation of T-Type Ca2+ Channels in Sensory Neurons Contributes to Acute Anti-Nociceptive Effect of Substance P

Published:2016-08-10 Issue:5 Volume:25 Page:233-251
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Huang Dongyang¹,Huang Sha¹,Gao Haixia¹²,Liu Yani¹,Qi Jinlong¹,Chen Pingping¹,Wang Caixue¹,Scragg Jason L.³,Vakurov Alexander²,Peers Chris³,Du Xiaona¹,Zhang Hailin¹,Gamper Nikita¹²

Affiliation:

1. Department of Pharmacology, Hebei Medical University, Shijiazhuang, P.R. China.

2. School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.

3. Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), Faculty of Medicine and Health, University of Leeds, Leeds, United Kingdom.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/ars.2015.6560

Reference76 articles.

1. Effects of substance P on excitability and ionic currents of normal and axotomized rat dorsal root ganglion neurons

2. Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone

3. Silencing of the Cav3.2 T-type calcium channel gene in sensory neurons demonstrates its major role in nociception

4. Carbon monoxide inhibition of Cav3.2 T‐type Ca 2+ channels reveals tonic modulation by thioredoxin

5. Morphological characterization of substance P receptor-immunoreactive neurons in the rat spinal cord and trigeminal nucleus caudalis

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