Preferential Extracellular Generation of the Active Parkinsonian Toxin MPP+ by Transporter-Independent Export of the Intermediate MPDP+-Reference-Cited by-同舟云学术

Preferential Extracellular Generation of the Active Parkinsonian Toxin MPP+ by Transporter-Independent Export of the Intermediate MPDP+

Published:2015-11 Issue:13 Volume:23 Page:1001-1016
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Schildknecht Stefan¹,Pape Regina¹,Meiser Johannes²,Karreman Christiaan¹,Strittmatter Tobias³,Odermatt Meike¹,Cirri Erica¹,Friemel Anke³,Ringwald Markus⁴,Pasquarelli Noemi⁵,Ferger Boris⁵,Brunner Thomas¹,Marx Andreas³,Möller Heiko M.⁶,Hiller Karsten²,Leist Marcel¹

Affiliation:

1. Department of Biology, University of Konstanz, Konstanz, Germany.

2. Metabolomics Junior Research Group, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-Belval, Luxembourg.

3. Department of Chemistry and Konstanz Research School Chemical Biology, University of Konstanz, Konstanz, Germany.

4. MCAT GmbH, Konstanz, Germany.

5. CNS Disease Research, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.

6. Institute of Chemistry, University of Potsdam, Potsdam, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/ars.2015.6297

Reference56 articles.

1. Metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine by Mitochondrion-targeted Cytochrome P450 2D6

2. Experimental models of Parkinson's disease

3. V. Potential bioactivation pathways for the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

Cited by 40 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Potential Therapeutic Approach using Aromatic l-amino Acid Decarboxylase and Glial-derived Neurotrophic Factor Therapy Targeting Putamen in Parkinson's Disease;Current Gene Therapy;2024-08

2. Modeling ferroptosis in human dopaminergic neurons: Pitfalls and opportunities for neurodegeneration research;Redox Biology;2024-07

3. Neuroprotective effect of marrubiin against MPTP-induced experimental Parkinson’s disease in male wistar rats;Toxicology Mechanisms and Methods;2024-06-10

4. Definition of the Neurotoxicity-Associated Metabolic Signature Triggered by Berberine and Other Respiratory Chain Inhibitors;Antioxidants;2023-12-28

5. Promising influences of caffeic acid and caffeic acid phenethyl ester against natural and chemical toxins: A comprehensive and mechanistic review;Journal of Functional Foods;2023-08