To Genotype or Phenotype for Personalized Medicine? CYP450 Drug Metabolizing Enzyme Genotype–Phenotype Concordance and Discordance in the Ecuadorian Population-Reference-Cited by-同舟云学术

To Genotype or Phenotype for Personalized Medicine? CYP450 Drug Metabolizing Enzyme Genotype–Phenotype Concordance and Discordance in the Ecuadorian Population

Published:2016-12 Issue:12 Volume:20 Page:699-710
ISSN:1557-8100
Container-title:OMICS: A Journal of Integrative Biology
language:en
Short-container-title:OMICS: A Journal of Integrative Biology

Author:

De Andrés Fernando¹,Terán Santiago²,Hernández Francisco³,Terán Enrique²,LLerena Adrián¹

Affiliation:

1. CICAB Clinical Research Centre, Extremadura University Hospital and Medical School, Badajoz, Spain.

2. Colegio de Ciencias de la Salud, Universidad San Francisco de Quito, Quito, Ecuador.

3. Facultad de Ciencias Médicas, Universidad Estatal de Guayaquil, Guayaquil, Ecuador.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine,Biochemistry,Biotechnology

Link

http://www.liebertpub.com/doi/pdf/10.1089/omi.2016.0148

Reference68 articles.

1. Dextromethorphan metabolic phenotyping in an Iranian population

2. Genetic Polymorphism of CYP1A2 in Ethiopians Affecting Induction and Expression: Characterization of Novel Haplotypes with Single-Nucleotide Polymorphisms in Intron 1

3. High frequency and founder effect of the CYP3A4*20 loss-of-function allele in the Spanish population classifies CYP3A4 as a polymorphic enzyme

4. Whole-Exome Sequencing Reveals Defective CYP3A4 Variants Predictive of Paclitaxel Dose-Limiting Neuropathy

5. CYP2C9 genetic variants and losartan oxidation in a Turkish population

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