4-Hydroxybenzoic Acid and β-Sitosterol from Cucurbita ficifolia Act as Insulin Secretagogues, Peroxisome Proliferator-Activated Receptor-Gamma Agonists, and Liver Glycogen Storage Promoters: In Vivo, In Vitro, and In Silico Studies-Reference-Cited by-同舟云学术

4-Hydroxybenzoic Acid and β-Sitosterol from Cucurbita ficifolia Act as Insulin Secretagogues, Peroxisome Proliferator-Activated Receptor-Gamma Agonists, and Liver Glycogen Storage Promoters: In Vivo, In Vitro, and In Silico Studies

Published:2022-06-01 Issue:6 Volume:25 Page:588-596
ISSN:1096-620X
Container-title:Journal of Medicinal Food
language:en
Short-container-title:Journal of Medicinal Food

Author:

Rosiles-Alanis Wendoline¹,Zamilpa Alejandro²,García-Macedo Rebeca³,Zavala-Sánchez Miguel A.⁴,Hidalgo-Figueroa Sergio⁵,Mora-Ramiro Beatriz⁶,Román-Ramos Rubén⁶,Estrada-Soto Samuel E.⁷,Almanza-Perez Julio C.⁶

Affiliation:

1. Postgraduate degree programme in Experimental Biology, DCBS, Autonomous Metropolitan University-Iztapalapa, Mexico City, Mexico.

2. Southern Biomedical Research Center (CIBIS), Mexican Social Security Institute, Xochitepec, Mexico.

3. Medical Investigation Unit in Biochemistry, Specialty Hospital, XXI Century National Medical Center, Mexican Social Security Institute (IMSS), Mexico City, Mexico.

4. Biological Systems Dept., DCBS, Autonomous Metropolitan University-Xochimilco, Mexico City, Mexico.

5. CONACyT, IPICYT/Consortium for Research, Innovation and Development for Arid Zones, San Luis Potosí, Mexico.

6. Health Science Dept., DCBS, Autonomous Metropolitan University-Iztapalapa, Mexico City, Mexico.

7. Pharmacy Faculty, Autonomous University of the State of Morelos, Cuernavaca, Mexico.

Publisher

Mary Ann Liebert Inc

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Link

https://www.liebertpub.com/doi/pdf/10.1089/jmf.2021.0071

Reference23 articles.

1. Mexican plants with hypoglycaemic effect used in the treatment of diabetes

2. C ucurbita ficifolia Bouché (Cucurbitaceae) and D-chiro-inositol modulate the redox state and inflammation in 3T3-L1 adipocytes

3. Cucurbita ficifolia Bouché increases insulin secretion in RINm5F cells through an influx of Ca2+ from the endoplasmic reticulum

4. CHEMICAL CHARACTERIZATION OF A HYPOGLYCEMIC EXTRACT FROM CUCURBITA FICIFOLIA BOUCHE THAT INDUCES LIVER GLYCOGEN ACCUMULATION IN DIABETIC MICE

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