Modulation of CD3-γ Gene Expression after HIV Type 1 Infection of the WE17/10 T Cell Line Is Progressive and Occurs in Concert with Decreased Production of Viral p24 Antigen-Reference-Cited by-同舟云学术

Modulation of CD3-γ Gene Expression after HIV Type 1 Infection of the WE17/10 T Cell Line Is Progressive and Occurs in Concert with Decreased Production of Viral p24 Antigen

Published:1996-05-20 Issue:8 Volume:12 Page:715-725
ISSN:0889-2229
Container-title:AIDS Research and Human Retroviruses
language:en
Short-container-title:AIDS Research and Human Retroviruses

Author:

WILLARD-GALLO KAREN E.,DELMELLE-WIBAUT CHRISTINE,SEGURA-ZAPATA IRIS,JANSSENS MICHEL,WILLEMS LUC,KETTMANN RICHARD

Publisher

Mary Ann Liebert Inc

Subject

Infectious Diseases,Virology,Immunology

Link

http://www.liebertpub.com/doi/pdf/10.1089/aid.1996.12.715

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1. Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging.

2. Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men. HIV affects the immune system before CD4+ T helper cell depletion occurs.

3. HIV-1-Infected T Cells Show a Selective Signaling Defect After Perturbation of CD3/Antigen Receptor

4. Selective loss of T cell functions in different stages of HIV infection Early loss ofanti-CD3-induced T cell proliferation followed by decreased anti-CD3-induced cytotoxic T lymphocyte generation in AIDS-related complex and AIDS

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1. Progressive loss of CD3 expression after HTLV-I infection results from chromatin remodeling affecting all the CD3 genes and persists despite early viral genes silencing;Virology Journal;2007-09-06

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