Update December 2022

Author:

Blei Francine1

Affiliation:

1. Hemangioma and Vascular Malformations Program, Hassenfeld Children's Hospital at NYU Langone, Grossman School of Medicine, New York, New York, USA.

Publisher

Mary Ann Liebert Inc

Subject

Cardiology and Cardiovascular Medicine

Reference100 articles.

1. Update December 2022 Francine Blei, MD, MBA

2. Dissection of murine collecting lymphatic vessels for imaging, single-cell analysis, and tissue culture of lymphatic muscle cells

3. Balasubramaniyan, M., et al. (2022). ``Immunomodulatory effects of chitosan nanoparticles as vaccine delivery agent against Iymphatic filariasis through mucosal immunization.'' Int J Biol Macromol 222(Pt B): 2392-2398. EPub 2022/10/12 Lymphatic filariasis is a parasitic disease caused by nematodes affecting millions of individuals in the tropical region. The complex life cycle of the filarial parasite eludes protective measures such as chemotherapy and vector control. Vaccination through recombinant proteins stands as one of the safe and most effective methods. The filarial antigens Brugia malayi Thioredoxin (TRX) and abundant larval transcript-2 (ALT-2) can induce recognizable levels of protection in murine animal models. Chitosan is a safe, non-toxic material ubiquitously served as an efficient carrier and an adjuvant. The present study was attempted to enhance the immune efficacy of filarial antigens using chitosan nanoparticles (CN) through mucosal routes of immunization. Our study showed that oral immunization was able to produce enhanced humoral response and balanced Th1/Th2 antibody isotype response for the recombinant antigens compared to intranasal routes.

4. Jo, M., et al. (2022). ``Impact of Goreisan components on rat mesenteric collecting Iymphatic vessel pumping.'' Microcirculation: e12788. EPub 2022/09/29

5. Subconjunctival Lymphatics Respond to VEGFC and Anti-Metabolites in Rabbit and Mouse Eyes

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