Differential Uptake of Antisense Oligonucleotides in Mouse Hepatocytes and Macrophages Revealed by Simultaneous Two-Photon Excited Fluorescence and Coherent Raman Imaging-Reference-Cited by-同舟云学术

Differential Uptake of Antisense Oligonucleotides in Mouse Hepatocytes and Macrophages Revealed by Simultaneous Two-Photon Excited Fluorescence and Coherent Raman Imaging

Published:2021-11-19 Issue: Volume: Page:
ISSN:2159-3337
Container-title:Nucleic Acid Therapeutics
language:en
Short-container-title:Nucleic Acid Therapeutics

Author:

Mukherjee Prabuddha¹²^ORCID,Aksamitiene Edita¹²,Alex Aneesh¹³,Shi Jindou¹²⁴,Bera Kajari¹²^ORCID,Zhang Chi¹²,Spillman Darold R.¹²,Marjanovic Marina¹²⁵⁶,Fazio Michael⁷,Seth Punit P.⁷^ORCID,Frazier Kendall³,Hood Steve R.¹⁸,Boppart Stephen A.¹²⁴⁵⁶^ORCID

Affiliation:

1. GSK Center for Optical Molecular Imaging and University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

2. Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

3. In vitro/In vivo Translation, Research, GlaxoSmithKline, Collegeville, Pennsylvania, USA.

4. Department of Electrical and Computer Engineering and University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

5. Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

6. Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

7. Ionis Pharmaceuticals, Inc., Carlsbad, California, USA.

8. In vitro/In vivo Translation, Research, GlaxoSmithKline, Stevenage, United Kingdom.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://www.liebertpub.com/doi/pdf/10.1089/nat.2021.0059

Reference52 articles.

1. Therapeutic Antisense Oligonucleotides Are Coming of Age

2. Antisense technology: an overview and prospectus

3. The delivery of therapeutic oligonucleotides

4. ASGR1andASGR2, the Genes that Encode the Asialoglycoprotein Receptor (Ashwell Receptor), Are Expressed in Peripheral Blood Monocytes and Show Interindividual Differences in Transcript Profile

5. The asialoglycoprotein receptor: a model for endocytic transport receptors

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