Programmed Instability of Ligand Conjugation Manifold for Efficient Hepatocyte Delivery of Therapeutic Oligonucleotides-Reference-Cited by-同舟云学术

Programmed Instability of Ligand Conjugation Manifold for Efficient Hepatocyte Delivery of Therapeutic Oligonucleotides

Published:2021-12-01 Issue:6 Volume:31 Page:404-416
ISSN:2159-3337
Container-title:Nucleic Acid Therapeutics
language:en
Short-container-title:Nucleic Acid Therapeutics

Author:

Terada Chisato¹,Wada Fumito²³,Uchida Mei¹,Yasutomi Yukari¹,Oh Kaho¹,Kawamoto Seiya¹,Kayaba Yukina¹,Yamayoshi Asako¹,Harada-Shiba Mariko²,Obika Satoshi³^ORCID,Yamamoto Tsuyoshi¹^ORCID

Affiliation:

1. Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.

2. Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute, Suita, Japan.

3. Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Japan.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://www.liebertpub.com/doi/pdf/10.1089/nat.2021.0036

Reference59 articles.

1. Delivery of Oligonucleotides to the Liver with GalNAc: From Research to Registered Therapeutic Drug

2. Preclinical and Clinical Advances of GalNAc-Decorated Nucleic Acid Therapeutics

3. Bioconjugated Oligonucleotides: Recent Developments and Therapeutic Applications

4. Targeted delivery of antisense oligonucleotides to pancreatic β-cells

5. The Binding of Desialylated Glycoproteins by Plasma Membranes of Rat Liver

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