Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha-Reference-Cited by-同舟云学术

Modeling Nonalcoholic Fatty Liver Disease with Human Pluripotent Stem Cell-Derived Immature Hepatocyte-Like Cells Reveals Activation of PLIN2 and Confirms Regulatory Functions of Peroxisome Proliferator-Activated Receptor Alpha

Published:2016-08 Issue:15 Volume:25 Page:1119-1133
ISSN:1547-3287
Container-title:Stem Cells and Development
language:en
Short-container-title:Stem Cells and Development

Author:

Graffmann Nina¹,Ring Sarah¹,Kawala Marie-Ann¹,Wruck Wasco¹,Ncube Audrey¹,Trompeter Hans-Ingo²,Adjaye James¹

Affiliation:

1. Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

2. Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Developmental Biology,Hematology

Link

https://www.liebertpub.com/doi/pdf/10.1089/scd.2015.0383

Reference48 articles.

1. Human Fatty Liver Disease: Old Questions and New Insights

2. Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

3. From fatty liver to fibrosis: A tale of “second hit”

4. Role of lipid droplet proteins in liver steatosis

5. Cell biology of lipid droplets

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