Hepatic Stellate Cell–Targeted Delivery of Hepatocyte Growth Factor Transgene via Bile Duct Infusion Enhances Its Expression at Fibrotic Foci to Regress Dimethylnitrosamine-Induced Liver Fibrosis-Reference-Cited by-同舟云学术

Hepatic Stellate Cell–Targeted Delivery of Hepatocyte Growth Factor Transgene via Bile Duct Infusion Enhances Its Expression at Fibrotic Foci to Regress Dimethylnitrosamine-Induced Liver Fibrosis

Published:2013-05 Issue:5 Volume:24 Page:508-519
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Narmada Balakrishnan Chakrapani¹²³⁴,Kang Yuzhan⁵,Venkatraman Lakshmi²⁶,Peng Qiwen³⁶,Sakban Rashidah Binte⁴,Nugraha Bramasta¹²³,Jiang Xuan⁷,Bunte Ralph M.⁸,So Peter T.C.⁵⁶⁹¹⁰,Tucker-Kellogg Lisa²⁶,Mao Hai-Quan⁷,Yu Hanry¹²³⁴⁵

Affiliation:

1. NUS Graduate School for Integrative Science and Engineering; National University of Singapore, Singapore 117456, Republic of Singapore.

2. Mechanobiology Institute, Temasek Laboratories; National University of Singapore, Singapore 117411, Republic of Singapore.

3. Institute of Bioengineering and Nanotechnology, Agency for Science, Technology and Research (A*Star), Singapore 117599, Republic of Singapore.

4. Department of Physiology; National University of Singapore, Singapore 138669, Republic of Singapore.

5. Singapore-MIT Alliance for Research and Technology, Singapore 138602, Republic of Singapore.

6. Singapore-MIT Alliance, Singapore 117576, Republic of Singapore.

7. Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218-2681.

8. Department of Pathology, Duke-NUS Graduate Medical School, Singapore 169857, Republic of Singapore.

9. Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.

10. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2012.158

Reference36 articles.

1. Effects of a New Bioactive Lipid-Based Drug Carrier on Cultured Hepatic Stellate Cells and Liver Fibrosis in Bile Duct-Ligated Rats

2. Liver fibrosis

3. Proapoptotic Bid is required for pulmonary fibrosis

4. Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery

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