Adoptive Immunotherapy with Redirected T Cells Produces CCR7− Cells That Are Trapped in the Periphery and Benefit from Combined CD28-OX40 Costimulation-Reference-Cited by-同舟云学术

Adoptive Immunotherapy with Redirected T Cells Produces CCR7− Cells That Are Trapped in the Periphery and Benefit from Combined CD28-OX40 Costimulation

Published:2013-03 Issue:3 Volume:24 Page:259-269
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Hombach Andreas A.¹,Chmielewski Markus¹,Rappl Gunter¹,Abken Hinrich¹

Affiliation:

1. Center for Molecular Medicine Cologne (CMMC) and Department I Internal Medicine, University of Cologne, 50931 Cologne, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2012.247

Reference40 articles.

1. Tuning tumor-specific T-cell activation: a matter of costimulation?

2. Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

3. Cyclophosphamide Enhances the Antitumor Efficacy of Adoptively Transferred Immune Cells through the Induction of Cytokine Expression, B-Cell and T-Cell Homeostatic Proliferation, and Specific Tumor Infiltration

4. Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics

5. Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains

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