Anti-HIV Drug-Combination Nanoparticles Enhance Plasma Drug Exposure Duration as Well as Triple-Drug Combination Levels in Cells Within Lymph Nodes and Blood in Primates-Reference-Cited by-同舟云学术

Anti-HIV Drug-Combination Nanoparticles Enhance Plasma Drug Exposure Duration as Well as Triple-Drug Combination Levels in Cells Within Lymph Nodes and Blood in Primates

Published:2015-01 Issue:1 Volume:31 Page:107-114
ISSN:0889-2229
Container-title:AIDS Research and Human Retroviruses
language:en
Short-container-title:AIDS Research and Human Retroviruses

Author:

Freeling Jennifer P.¹,Koehn Josefin¹,Shu Cuiling¹,Sun Jianguo¹²,Ho Rodney J.Y.¹

Affiliation:

1. Department of Pharmaceutics, University of Washington, Seattle, Washington.

2. Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, Jiangsu, China.

Publisher

Mary Ann Liebert Inc

Subject

Infectious Diseases,Virology,Immunology

Link

http://www.liebertpub.com/doi/pdf/10.1089/aid.2014.0210

Reference31 articles.

1. Re-emergence of HIV after stopping therapy

2. Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure

3. Lymph nodes harbor viral reservoirs that cause rebound of plasma viremia in SIV-infected macaques upon cessation of combined antiretroviral therapy

4. Residual Human Immunodeficiency Virus Type 1 RNA in Lymphoid Tissue of Patients with Sustained Plasma RNA of <200 Copies/mL

5. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells

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