Molecular Mechanisms Involved in Enhancing HO-1 Expression: De-Repression by Heme and Activation by Nrf2, The "One-Two" Punch
Author:
Affiliation:
1. Department of Pharmacology and Toxicology, College of Medicine, Inha University, Incheon, South Korea.
2. Present address: Department of Biochemistry, Faculty of Science, Burapha University, Chonburi, Thailand, 20131.
Publisher
Mary Ann Liebert Inc
Subject
Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry
Link
http://www.liebertpub.com/doi/pdf/10.1089/ars.2005.7.1674
Reference123 articles.
1. Multiple elements within the 5' distal enhancer of the mouse heme oxygenase-1 gene mediate induction by heavy metals.
2. Transcriptional Activation of the Heme Oxygenase Gene by Heme and Cadmium in Mouse Hepatoma Cells
3. Identification of a Second Region Upstream of the Mouse Heme Oxygenase-1 Gene That Functions as a Basal Level and Inducer-dependent Transcription Enhancer
4. Nrf2, a Cap'n'Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene
5. Mechanism of Heme Oxygenase-1 Gene Activation by Cadmium in MCF-7 Mammary Epithelial Cells
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