Evidence for a Simplified View of Autoantibody Interactions with the Thyrotropin Receptor
Author:
Affiliation:
1. Autoimmune Disease Unit, Cedars-Sinai Research Institute, Los Angeles, California
2. Research Institute for Production Development, Kyoto, Japan
3. Department of Pharmacology, University of Nagasaki School of Medicine, Nagasaki, Japan
Publisher
Mary Ann Liebert Inc
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://www.liebertpub.com/doi/pdf/10.1089/105072502753522347
Reference33 articles.
1. The Thyrotropin (TSH)-Releasing Hormone Receptor: Interaction with TSH and Autoantibodies
2. Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors.
3. Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function.
4. Immunoglobulins from Graves' disease patients interact with different sites on TSH receptor/LH-CG receptor chimeras than either TSH or immunoglobulins from idiopathic myxedema patients
5. Thyroid stimulatory autoantibodies in different patients with autoimmune thyroid disease do not all recognize the same components of the human thyrotropin receptor: selective role of receptor amino acids Ser25-Glu30
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