A Configurable Three-Dimensional Microenvironment in a Microfluidic Channel for Primary Hepatocyte Culture-Reference-Cited by-同舟云学术

A Configurable Three-Dimensional Microenvironment in a Microfluidic Channel for Primary Hepatocyte Culture

Published:2005-04 Issue:2 Volume:3 Page:169-176
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Toh Yi-Chin¹²,Ng Susanne¹²,Khong Yuet Mei¹³,Samper Victor¹,Yu Hanry¹⁴

Affiliation:

1. Institute of Bioengineering and Nanotechnology, Singapore.

2. NUS Graduate School of Integrative Sciences and Engineering, NUS Graduate Program in Bioengineering, National University of Singapore, Singapore.

3. NUS Graduate Program in Bioengineering, National University of Singapore, Singapore.

4. NUS Graduate School of Integrative Sciences and Engineering, NUS Graduate Program in Bioengineering, and Department of Physiology, National University of Singapore, Singapore.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2005.3.169

Reference23 articles.

1. Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation

2. Problems in using isolated and cultured hepatocytes for xenobiotic metabolism/metabolism-based toxicity testing—Solutions?

3. Evaluation of the effect of culture configuration on morphology, survival time, antioxidant status and metabolic capacities of cultured rat hepatocytes

4. Requirement of 3D extracellular network for maintenance of mature hepatocyte morphology and suppression of alpha-fetoprotein synthesis in vitro

5. Hepatocyte Encapsulation for Enhanced Cellular Functions

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