Optimization of the Generation and Propagation of Gutless Adenoviral Vectors
Author:
Affiliation:
1. Genetic Therapy, Inc. (A Novartis Company), Gaithersburg, MD 20878
2. Advanced Vision Therapies, Inc., Rockville, MD 20854
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/10430340360535797
Reference20 articles.
1. Gutted adenoviral vector growth using E1/E2b/E3-deleted helper viruses
2. A novel system for the production of fully deleted adenovirus vectors that does not require helper adenovirus
3. New Helper Cells and Matched Early Region 1-Deleted Adenovirus Vectors Prevent Generation of Replication-Competent Adenoviruses
4. Elimination of both E1 and E2 from adenovirus vectors further improves prospects for in vivo human gene therapy
5. Construction of adenovirus vectors through Cre-lox recombination
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