Lentivirus-Mediated Expression of Mutant MGMTP140KProtects Human CD34+Cells Against the Combined Toxicity ofO6-Benzylguanine and 1,3-Bis(2-Chloroethyl)-Nitrosourea or Temozolomide-Reference-Cited by-同舟云学术

Lentivirus-Mediated Expression of Mutant MGMTP140KProtects Human CD34+Cells Against the Combined Toxicity ofO6-Benzylguanine and 1,3-Bis(2-Chloroethyl)-Nitrosourea or Temozolomide

Published:2004-08 Issue:8 Volume:15 Page:758-769
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Chinnasamy Dhanalakshmi¹,Fairbairn Leslie J.²,Neuenfeldt James¹,Treisman Jonathan S.¹,Hanson John P.¹,Margison Geoffrey P.³,Chinnasamy Nachimuthu¹

Affiliation:

1. Vince Lombardi Gene Therapy Laboratory, Immunotherapy Program, St. Luke's Medical Center, Milwaukee, WI 53151.

2. Cancer Research UK Gene Therapy Group, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester M20 4BX, UK.

3. Cancer Research UK Carcinogenesis Group, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester M20 4BX, UK.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/1043034041648417

Reference50 articles.

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3. O 6-Benzylguanine Potentiates the In Vivo Toxicity and Clastogenicity of Temozolomide and BCNU in Mouse Bone Marrow

4. Chemoprotective gene transfer II: multilineage in vivo protection of haemopoiesis against the effects of an antitumour agent by expression of a mutant human O6-alkylguanine-DNA alkyltransferase

5. Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins

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