Biolistic-Mediated Interleukin 4 Gene Transfer Prevents the Onset of Type 1 Diabetes-Reference-Cited by-同舟云学术

Biolistic-Mediated Interleukin 4 Gene Transfer Prevents the Onset of Type 1 Diabetes

Published:2000-08-10 Issue:12 Volume:11 Page:1647-1656
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Cameron Mark J.¹,Strathdee Craig A.²,Holmes Kevin D.²,Arreaza Guillermo A.¹,Dekaban Gregory A.²,Delovitch Terry L.³

Affiliation:

1. Autoimmunity/Diabetes Group, John P. Robarts Research Institute, London, Ontario N6G 2V4, Canada and Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada

2. Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada and Gene Therapy and Molecular Virology Group, John P. Robarts Research Institute, London, Ontario N6G 2V4, Canada

3. Autoimmunity/Diabetes Group, John P. Robarts Research Institute, London, Ontario N6G 2V4, Canada; Department of Microbiology and Immunology, University of Western Ontario, London, Ontario N6A 5C1, Canada and Department of Medicine, University of Western Ontario, London, Ontario N6A 5C1, Canada.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/10430340050111304

Reference32 articles.

1. Neonatal activation of CD28 signaling overcomes T cell anergy and prevents autoimmune diabetes by an IL-4-dependent mechanism.

2. Insulin B-chain reactive CD4+ regulatory T-cells induced by oral insulin treatment protect from type 1 diabetes by blocking the cytokine secretion and pancreatic infiltration of diabetogenic effector T-cells.

3. Human CD8 + T Cell Responses to EBV EBNA1: HLA Class I Presentation of the (Gly-Ala)–Containing Protein Requires Exogenous Processing

4. Crystal structure of the DNA-binding domain of the Epstein-Barr virus origin-binding protein EBNA1

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