Acute Toxicity After High-Dose Systemic Injection of Helper-Dependent Adenoviral Vectors into Nonhuman Primates
Author:
Affiliation:
1. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030
2. Southwest Foundation for Biomedical Research, San Antonio, TX 78227
3. Department of Pathology, Baylor College of Medicine, Houston, TX 77030
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/10430340460732445
Reference33 articles.
1. Evaluation of the Duration of Human Factor VIII Expression in Nonhuman Primates After Systemic Delivery of an Adenoviral Vector
2. Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector
3. Adenoviral Vector-Mediated Expression of Physiologic Levels of Human Factor VIII in Nonhuman Primates
4. Production and characterization of human 293 cell lines expressing the site-specific recombinase Cre
5. Complement activation by recombinant adenoviruses
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