Immunization of Patients with Malignant Melanoma with Autologous CD34+Cell-Derived Dendritic Cells TransducedEx Vivowith a Recombinant Replication-Deficient Vaccinia Vector Encoding the Human Tyrosinase Gene: A Phase I Trial-Reference-Cited by-同舟云学术

Immunization of Patients with Malignant Melanoma with Autologous CD34+Cell-Derived Dendritic Cells TransducedEx Vivowith a Recombinant Replication-Deficient Vaccinia Vector Encoding the Human Tyrosinase Gene: A Phase I Trial

Published:2003-09-20 Issue:14 Volume:14 Page:1347-1360
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Di Nicola Massimo¹,Carlo-Stella Carmelo¹,Anichini Andrea²,Mortarini Roberta²,Guidetti Anna¹,Tragni Gabrina³,Gallino Francesco⁴,Del Vecchio Michele⁵,Ravagnani Fernando⁶,Morelli Daniele⁶,Chaplin Paul⁷,Arndtz Nathaly⁸,Sutter Gerd⁹,Drexler Ingo⁹,Parmiani Giorgio⁷,Cascinelli Natale¹⁰,Gianni Alessandro M.¹

Affiliation:

1. Cristina Gandini Bone Marrow Transplantation Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan I-20133, Italy

2. Human Tumor Immunobiology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan I-20133, Italy

3. Anatomic Pathology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan I-20133, Italy

4. Colorectal Surgery Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan I-20133, Italy

5. Medical Oncology B Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan I-20133, Italy

6. Laboratory Medicine Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan I-20133, Italy

7. Human Tumor Immunotherapy Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan I-20133, Italy

8. Bavarian Nordic Research Institute, Munich 81675, Germany

9. Institute for Molecular Virology, GSF - National Research Center, Munich 85764, Germany

10. Scientific Direction, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan I-20133, Italy

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/104303403322319426

Reference83 articles.

1. Therapeutic Antitumor Response After Immunization with an Admixture of Recombinant Vaccinia Viruses Expressing a Modified MUC1 Gene and the Murine T-Cell Costimulatory Molecule B7

2. Dendritic cells generated from peripheral blood transfected with human tyrosinase induce specific T cell activation

3. Limited Antitumor T Cell Response in Melanoma Patients Vaccinated with Interleukin-2 Gene-Transduced Allogeneic Melanoma Cells

4. Prognostic Factors Analysis of 17,600 Melanoma Patients: Validation of the American Joint Committee on Cancer Melanoma Staging System

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