1. Department of Biology, McMaster University, Hamilton, Ontario, L8N 3Z5 Canada
2. Department of Pediatrics, McMaster University, Hamilton, Ontario, L8N 3Z5 Canada; Department of Genetics, University of Alberta, Alberta, Canada
3. Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110
4. Department of Biology; Department of Pediatrics, McMaster University, Hamilton, Ontario, L8N 3Z5 Canada