Therapeutic Vaccination against Metastatic Carcinoma by Expression-Modulated and Immunomodified Autologous Tumor Cells: A First Clinical Phase I/II Trial

Author:

Wittig Burghardt1,Märten Angela2,Dorbic Tomislav3,Weineck Silvia2,Min Heshon2,Niemitz Sigrun4,Trojaneck Beate4,Flieger Dimitri2,Kruopis Susanne3,Albers Andreas3,Löffel Jürgen4,Neubauer Andreas5,Albers Peter6,Müller Stefan6,Sauerbruch Tilman2,Bieber Thomas7,Huhn Dieter4,Schmidt-Wolf Ingo G.H.2

Affiliation:

1. Centrum Somatische Gentherapie, Fachbereich Humanmedizin, Freie Universität Berlin, 14195 Berlin, Germany; Mologen Holding AG, 14195 Berlin, Germany.

2. Department of Medicine, University of Bonn, 53105 Bonn, Germany.

3. Centrum Somatische Gentherapie, Fachbereich Humanmedizin, Freie Universität Berlin, 14195 Berlin, Germany.

4. Department of Medicine, Division of Hematology/Oncology, Humboldt-Universität zu Berlin, 13353 Berlin, Germany.

5. Department of Medicine, Klinikum der Philipps-Universität, 35033 Marburg, Germany.

6. Department of Urology, University of Bonn, 53105 Bonn, Germany.

7. Department of Dermatology, University of Bonn, 53105 Bonn, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

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