Effect of Promoters and Enhancers on Expression, Transgene DNA Persistence, and Hepatotoxicity After Adenoviral Gene Transfer of Human Apolipoprotein A-I-Reference-Cited by-同舟云学术

Effect of Promoters and Enhancers on Expression, Transgene DNA Persistence, and Hepatotoxicity After Adenoviral Gene Transfer of Human Apolipoprotein A-I

Published:2002-05 Issue:7 Volume:13 Page:829-840
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Van Linthout Sophie¹,Collen Désiré¹,De Geest Bart¹

Affiliation:

1. Center for Molecular and Vascular Biology, Campus Gasthuisberg, 3000 Leuven, Belgium.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/10430340252899000

Reference36 articles.

1. Efficient expression of protein coding genes from the murine U1 small nuclear RNA promoters.

2. Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo

3. Regulatory squelching

4. Modulation of the Inflammatory Properties and Hepatotoxicity of Recombinant Adenovirus Vectors by the Viral E4 Gene Products

5. The human U snRNA promoter and enhancer do not direct synthesis of messenger RNA

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