Hammerhead Ribozyme as a Therapeutic Agent for Hyperlipidemia: Production of Truncated Apolipoprotein B and Hypolipidemic Effects in a Dyslipidemia Murine Model-Reference-Cited by-同舟云学术

Hammerhead Ribozyme as a Therapeutic Agent for Hyperlipidemia: Production of Truncated Apolipoprotein B and Hypolipidemic Effects in a Dyslipidemia Murine Model

Published:2000-11-20 Issue:17 Volume:11 Page:2415-2430
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Enjoji Munechika¹,Wang Fang²,Nakamuta Makoto¹,Chan Lawrence³,Teng Ba-Bie⁴

Affiliation:

1. Departments of Medicine and Cell Biology, Baylor College of Medicine, Houston, TX 77030; Department of Internal Medicine III, Kyushu University, Fukuoka 812-8582, Japan

2. Research Center for Human Genetics, Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas-Houston Health Science Center, Houston, TX 77030

3. Departments of Medicine and Cell Biology, Baylor College of Medicine, Houston, TX 77030

4. Departments of Medicine and Cell Biology, Baylor College of Medicine, Houston, TX 77030; Research Center for Human Genetics, Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas-Houston Health Science Center, Houston, TX 77030

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/104303400750038516

Reference65 articles.

1. Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

2. The Structure, Function and Application of the Hammerhead Ribozyme

3. Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective apo-B100.

4. Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice.

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