Phase I Trial of Intramuscular Injection of a Recombinant Adeno-Associated Virus Alpha 1-Antitrypsin (rAAV2-CB-hAAT) Gene Vector to AAT-Deficient Adults-Reference-Cited by-同舟云学术

Phase I Trial of Intramuscular Injection of a Recombinant Adeno-Associated Virus Alpha 1-Antitrypsin (rAAV2-CB-hAAT) Gene Vector to AAT-Deficient Adults

Published:2004-01 Issue:1 Volume:15 Page:93-128
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/10430340460732490

Reference115 articles.

1. The α1-antitrypsin gene and its deficiency states

2. Evaluation of the S-type of Alpha-1-Antitrypsin as anIn VivoandIn VitroInhibitor of Neutrophil Elastase

3. Use of a Highly Purified α1-Antitrypsin Standard to Establish Ranges for the Common Normal and Deficient α1-Antitrypsin Phenotypes

4. Emphysema of Early Onset Associated with a Complete Deficiency of Alpha-1-Antitrypsin (null homozygotes)

5. Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase.

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