Interleukin 12 Gene Therapy of Cancer by Peritumoral Injection of Transduced Autologous Fibroblasts: Outcome of a Phase I Study-Reference-Cited by-同舟云学术

Interleukin 12 Gene Therapy of Cancer by Peritumoral Injection of Transduced Autologous Fibroblasts: Outcome of a Phase I Study

Published:2001-04-10 Issue:6 Volume:12 Page:671-684
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Kang Won Ki¹,Park Chaehwa²,Yoon Hyunah Lee²,Kim Won Seog³,Yoon Sung-Soo³,Lee Mark H.⁴,Park Keunchil³,Kim Kihyun³,Jeong Hyun Sik³,Kim Jeong-A⁵,Nam Seok-Jin⁶,Yang Jung-Hyun⁶,Son Young-Ik⁷,Baek Chung-Hwan⁷,Han Jungho⁸,Ree Howe J.⁸,Lee Eil Soo⁹,Kim Sun Hee¹⁰,Kim Dae-Won¹⁰,Ahn Yong Chan¹¹,Huh Seung Jae¹¹,Choe Yeon Hyeon¹²,Lee Je-Ho¹³,Park Mary H.²,Kong Gyoung-Sun²,Park Eun-Young²,Kang Yoon-Koo¹⁴,Bang Yung-Jue¹⁵,Paik Nam-Sun¹⁶,Lee Soon Nam¹⁷,Kim Seon-Hee¹⁸,Kim Sunyoung¹⁸,Robbins Paul D.¹⁹,Tahara Hideaki¹⁹,Lotze Michael T.¹⁹,Park Chan H.⁴

Affiliation:

1. Cancer Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea and Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

2. Cancer Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

3. Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.

4. Cancer Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea and Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea.

5. Division of Hematology and Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea and Department of Medicine, St. Vincent's Hospital, Catholic University, Suwon 442-723, Korea

6. Department of General Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

7. Department of Otorhinolaryngology/Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

8. Department of Diagnostic Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

9. Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

10. Department of Clinical Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

11. Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

12. Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

13. Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, Korea

14. Department of Internal Medicine, Asan Medical Center, Ulsan University, Seoul 138-736, Korea

15. Department of Internal Medicine, Seoul National University Hospital, Seoul 110-744, Korea

16. Department of General Surgery, Korea Cancer Center, Seoul, 139-706, Korea

17. Department of Internal Medicine, Ewha Womans University Hospital, Seoul 110-126, Korea

18. Institute for Molecular Biology and Genetics, Seoul National University, Seoul 151-742, Korea

19. University of Pittsburgh School of Medicine, Pittsburgh, PA 15261

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/104303401300057388

Reference37 articles.

1. Antitumor and antimetastatic activity of interleukin 12 against murine tumors.

2. Role of Interferon-γ in Mediating the Antitumor Efficacy of Interleukin-12

3. Nitric oxide mediates tumor necrosis factor-α cytotoxicity in endothelial cells

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