Contribution of Plasmid DNA to Hepatotoxicity after Systemic Administration of Lipoplexes
Author:
Affiliation:
1. EPI-EMI 0115, CHU, UBO, BP 454, 29275 Brest Cedex, France
2. Laboratoire d'Anatomopathologie, CHU Morvan, 29200 Brest Cedex, France
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/104303401300057405
Reference23 articles.
1. Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trial
2. Modulation of the Inflammatory Properties and Hepatotoxicity of Recombinant Adenovirus Vectors by the Viral E4 Gene Products
3. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.
4. Systemic administration of cationic phosphonolipids/DNA complexes and the relationship between formulation and lung transfection efficiency
5. Cation Substitution in Cationic Phosphonolipids: A New Concept To Improve Transfection Activity and Decrease Cellular Toxicity
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