Phase I Dose Escalation Clinical Trial of Adenovirus Vector Carrying Osteocalcin Promoter-Driven Herpes Simplex Virus Thymidine Kinase in Localized and Metastatic Hormone-Refractory Prostate Cancer

Author:

Kubo Hiroyuki1,Gardner Thomas A.2,Wada Yoshitaka3,Koeneman Kenneth S.4,Gotoh Akinobu3,Yang Ling4,Kao Chinghai5,Lim So Dug6,Amin Mahul B.6,Yang Hua4,Black Margaret E.7,Matsubara Shigeji8,Nakagawa Masayuki9,Gillenwater Jay Y.4,Zhau Haiyen E.8,Chung Leland W.K.8

Affiliation:

1. Molecular Urology and Therapeutics Program, Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322; Department of Urology, University of Virginia Health System, Charlottesville, VA 22908

2. Department of Urology, Indiana University Medical Center, Indianapolis, IN 46202; Department of Urology, University of Virginia Health System, Charlottesville, VA 22908

3. Department of Urology, Kobe University School of Medicine, Kobe 650-0017, Japan

4. Department of Urology, University of Virginia Health System, Charlottesville, VA 22908

5. Department of Urology, Indiana University Medical Center, Indianapolis, IN 46202

6. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322

7. Department of Pharmaceutical Sciences, Washington State University, Pullman, WA 99164

8. Molecular Urology and Therapeutics Program, Department of Urology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA 30322

9. Department of Urology, Faculty of Medicine, Kagoshima University, Kagoshima 890-8506, Japan

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

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