NUDT15andTPMTGenetic Polymorphisms Are Related to Azathioprine Intolerance in Chinese Patients with Rheumatic Diseases
Author:
Affiliation:
1. Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
2. Department of Rheumatology and Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Publisher
Mary Ann Liebert Inc
Subject
Genetics(clinical),General Medicine
Link
https://www.liebertpub.com/doi/pdf/10.1089/gtmb.2018.0313
Reference22 articles.
1. Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease
2. NUDT15 R139C-related thiopurine leukocytopenia is mediated by 6-thioguanine nucleotide-independent mechanism in Japanese patients with inflammatory bowel disease
3. NUDT15 R139C causes thiopurine-induced early severe hair loss and leukopenia in Japanese patients with IBD
4. NUDT15 genotype distributions in the Korean population
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1. Implementation of NUDT15 Genotyping to Prevent Azathioprine‐Induced Leukopenia for Patients With Autoimmune Disorders in Chinese Population;Clinical Pharmacology & Therapeutics;2022-08-22
2. XDH genotypes through gene–gene interactions with NUDT15 affect azathioprine-induced leukopenia in Chinese patients;Pharmacogenomics;2022-08
3. Pharmacogenetics of Drug Therapies in Rheumatoid Arthritis;Methods in Molecular Biology;2022
4. Meta-Analysis of NUDT15 Genetic Polymorphism on Thiopurine-Induced Myelosuppression in Asian Populations;Frontiers in Pharmacology;2021-12-02
5. Importance of NUDT15 Polymorphisms in Thiopurine Treatments;Journal of Personalized Medicine;2021-08-10
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