The First Molecular Screening ofMLH1andMSH2Genes in Moroccan Colorectal Cancer Patients Shows a Relatively High Mutational Prevalence-Reference-Cited by-同舟云学术

The First Molecular Screening ofMLH1andMSH2Genes in Moroccan Colorectal Cancer Patients Shows a Relatively High Mutational Prevalence

Published:2018-08 Issue:8 Volume:22 Page:492-497
ISSN:1945-0265
Container-title:Genetic Testing and Molecular Biomarkers
language:en
Short-container-title:Genetic Testing and Molecular Biomarkers

Author:

Moufid Fatima Zahra¹²,Bouguenouch Laila¹³,El Bouchikhi Ihssane¹²,Chbani Laila³⁴,Iraqui Houssaini Mohamed²,Sekal Mohamed⁴,Belhassan Khadija¹,Bennani Bahia⁵,Ouldim Karim¹³

Affiliation:

1. Department of Medical Genetics and Oncogenetics, Centre Hospitalier Hassam II, Fez, Morocco.

2. Microbial Biotechnology Laboratory, Faculté des Sciences et Techniques, Université Sidi Mohammed Ben Abdellah, Fez, Morocco.

3. Laboratory of Biomedical and Translational Research, Faculté 3de Médecine et de Pharmacie de Fès, Université Sidi Mohammed Ben Abdellah, Fez, Morocco.

4. Pathological Anatomy and Molecular Pathology Service, Hassan II University Hospital, Fez, Morocco.

5. Microbiology and Molecular Biology Laboratory, Microorganisms Team, Genomics and Oncogene Factors, Faculté de Médecine et de Pharmacie de Fès, Université Sidi Mohammed Ben Abdellah, Fez, Morocco.

Publisher

Mary Ann Liebert Inc

Subject

Genetics (clinical),General Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/gtmb.2018.0067

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1. Immunohistochemical staining for p16 and BRAFV600E is useful to distinguish between sporadic and hereditary (Lynch syndrome-related) microsatellite instable colorectal carcinomas

2. Cost-Effectiveness Analysis of Different Genetic Testing Strategies for Lynch Syndrome in Taiwan

3. Prevalence of Lynch syndrome and Lynch-like syndrome among patients with colorectal cancer in a Japanese hospital-based population

4. Next-Generation Sequencing Panels for the Diagnosis of Colorectal Cancer and Polyposis Syndromes: A Cost-Effectiveness Analysis

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