Influenza A Virus Hemagglutinin Is Produced in Different Disulfide-Bonded States
Author:
Affiliation:
1. ACRF Centenary Cancer Research Centre, The Centenary Institute, Camperdown, New South Wales, Australia.
2. NHMRC Clinical Trials Centre, University of Sydney, Sydney, New South Wales, Australia.
Publisher
Mary Ann Liebert Inc
Subject
Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry
Link
https://www.liebertpub.com/doi/pdf/10.1089/ars.2021.0033
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1. Sindbis virus membrane fusion is mediated by reduction of glycoprotein disulfide bridges at the cell surface
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3. Disulfide Bond That Constrains the HIV-1 gp120 V3 Domain Is Cleaved by Thioredoxin
4. Protein-disulfide Isomerase-mediated Reduction of Two Disulfide Bonds of HIV Envelope Glycoprotein 120 Occurs Post-CXCR4 Binding and Is Required for Fusion
5. A substrate-driven allosteric switch that enhances PDI catalytic activity
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