RNA Interference-Mediated Gene Silencing of Pleiotrophin Through Polyethylenimine-Complexed Small Interfering RNAsIn VivoExerts Antitumoral Effects in Glioblastoma Xenografts-Reference-Cited by-同舟云学术

RNA Interference-Mediated Gene Silencing of Pleiotrophin Through Polyethylenimine-Complexed Small Interfering RNAsIn VivoExerts Antitumoral Effects in Glioblastoma Xenografts

Published:2006-07 Issue:7 Volume:17 Page:751-766
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Grzelinski Marius¹,Urban-Klein Beata¹,Martens Tobias²,Lamszus Katrin²,Bakowsky Udo³,Höbel Sabrina¹,Czubayko Frank¹,Aigner Achim¹

Affiliation:

1. Department of Pharmacology and Toxicology, Philipps-University School of Medicine, D-35033 Marburg, Germany.

2. Department of Neurosurgery, University Hospital Hamburg-Eppendorf, D-20246 Hamburg, Germany.

3. Department of Biopharmacy and Pharmaceutical Technology, Philipps-University School of Medicine, D-35033 Marburg, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2006.17.751

Reference56 articles.

1. Cytotoxicity of the novel anti-cancer drug rViscumin depends on HER-2 levels in SKOV-3 cells

2. Gene silencing through RNA interference (RNAi) in vivo: Strategies based on the direct application of siRNAs

3. Delivery of unmodified bioactive ribozymes by an RNA-stabilizing polyethylenimine (LMW-PEI) efficiently down-regulates gene expression

4. Immunolocalization of an FGF-binding protein reveals a widespread expression pattern during different stages of mouse embryo development

5. Marked increase of the growth factors pleiotrophin and fibroblast growth factor-2 in serum of testicular cancer patients

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