Comparative Analysis of Antisense Oligonucleotide Sequences for Targeted Skipping of Exon 51 During Dystrophin Pre-mRNA Splicing in Human Muscle-Reference-Cited by-同舟云学术

Comparative Analysis of Antisense Oligonucleotide Sequences for Targeted Skipping of Exon 51 During Dystrophin Pre-mRNA Splicing in Human Muscle

Published:2007-09 Issue:9 Volume:18 Page:798-810
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Arechavala-Gomeza V.¹,Graham I.R.²,Popplewell L.J.²,Adams A.M.³,Aartsma-Rus A.⁴,Kinali M.¹,Morgan J.E.¹,van Deutekom J.C.⁴⁵,Wilton S.D.³,Dickson G.²,Muntoni F.¹

Affiliation:

1. Department of Paediatrics, Imperial College, London W12ONN, United Kingdom.

2. School of Biological Sciences, Royal Holloway-University of London, Egham TW20 0EX, United Kingdom.

3. Centre for Neurological and Neuromuscular Disorders, Australian Neuromuscular Research Institute, University of Western Australia, Perth WA6009, Australia.

4. Center for Human and Clinical Genetics, Leiden University Medical Center, 2300RC Leiden, The Netherlands.

5. Prosensa, 2333AL Leiden, The Netherlands.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2006.061

Reference66 articles.

1. Antisense-mediated exon skipping: A versatile tool with therapeutic and research applications

2. Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy

3. Therapeutic antisense-induced exon skipping in cultured muscle cells from six different DMD patients