Adenoviral Type 35 and 26 Vectors with a Bidirectional Expression Cassette in the E1 Region Show an Improved Genetic Stability Profile and Potent Transgene-Specific Immune Response
Author:
Affiliation:
1. Janssen Vaccines and Prevention, Janssen Pharmaceutical Companies of Johnson & Johnson, Leiden, the Netherlands.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2017.023
Reference68 articles.
1. A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity
2. Safety and immunogenicity of a novel recombinant adenovirus type-5 vector-based Ebola vaccine in healthy adults in China: preliminary report of a randomised, double-blind, placebo-controlled, phase 1 trial
3. Novel Adenovirus-Based Vaccines Induce Broad and Sustained T Cell Responses to HCV in Man
4. A replication defective recombinant Ad5 vaccine expressing Ebola virus GP is safe and immunogenic in healthy adults
5. A recombinant adenovirus expressing immunodominant TB antigens can significantly enhance BCG-induced human immunity
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