A Retrospective Study of the Cytokine Profile Changes in Mice with FVIII Inhibitor Development After Adeno-Associated Virus–Mediated Gene Therapy in a Hemophilia A Mouse Model-Reference-Cited by-同舟云学术

A Retrospective Study of the Cytokine Profile Changes in Mice with FVIII Inhibitor Development After Adeno-Associated Virus–Mediated Gene Therapy in a Hemophilia A Mouse Model

Published:2018-03 Issue:3 Volume:29 Page:381-389
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Sun Junjiang¹²,Yuan Zhenhua²,Abajas Yasmina L.³,Szollosi Doreen E.⁴,Hu Genlin¹,Hua Baolai⁵⁶,Xiao Xiao²,Li Chengwen¹⁷

Affiliation:

1. Gene Therapy Center, University of North Carolina, Chapel Hill, North Carolina.

2. Division of Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina.

3. Pediatric Hematology Oncology, University of North Carolina, Chapel Hill, North Carolina.

4. Department of Pharmaceutical Sciences, University of Saint Joseph School of Pharmacy, Hartford, Connecticut.

5. Department of Hematology, Northern Jiangsu People's Hospital, Yangzhou, China.

6. Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

7. Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2017.094

Reference48 articles.

1. Anti-Inhibitor Coagulant Complex Prophylaxis in Hemophilia with Inhibitors

2. Inhibitory antibodies in hemophilia A

3. A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A

4. Polymorphisms in the TNFA gene and the risk of inhibitor development in patients with hemophilia A

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