NADPH Oxidases as Regulators of Tumor Angiogenesis: Current and Emerging Concepts
Author:
Affiliation:
1. Centre for Cancer Research, Monash Institute of Medical Research, Monash University, Victoria, Australia.
2. Vascular Biology and Immunopharmacology Group, Department of Pharmacology, Monash University, Victoria, Australia.
Publisher
Mary Ann Liebert Inc
Subject
Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry
Link
http://www.liebertpub.com/doi/pdf/10.1089/ars.2011.4489
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1. Overexpression of Pigment Epithelium-Derived Factor Decreases Angiogenesis and Inhibits the Growth of Human Malignant Melanoma Cells in Vivo
2. NADPH oxidase activity is required for endothelial cell proliferation and migration
3. Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1
4. Nox4 as the Major Catalytic Component of an Endothelial NAD(P)H Oxidase
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