Improved Denoising of Cryo-Electron Microscopy Micrographs with Simulation-Aware Pretraining

Author:

Yang Zhidong12ORCID,Li Hongjia3,Zang Dawei1,Han Renmin4,Zhang Fa5

Affiliation:

1. High Performance Computer Research Center, Institute of Computing Technology, Chinese Academy of Sciences, Beijing, China.

2. University of Chinese Academy of Sciences, Beijing, China.

3. Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana, USA.

4. Research Center for Mathematics and Interdisciplinary Sciences, Frontiers Science Center for Nonlinear Expectations (Ministry of Education), Shandong University, Qingdao, China.

5. School of Medical Technology, Beijing Institute of Technology, Beijing, China.

Publisher

Mary Ann Liebert Inc

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