Thermal Denaturation Assays in Chemical Biology
Author:
Affiliation:
1. Structural Genomics Consortium, University of Toronto, Toronto, Ontario, Canada.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/adt.2011.0390
Reference77 articles.
1. Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
2. High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery
3. The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability
4. Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery
5. Screening for Ligands Using a Generic and High-Throughput Light-Scattering-Based Assay
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