Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells-Reference-Cited by-同舟云学术

Splice-Switching Antisense Oligonucleotides as a Targeted Intrinsic Engineering Tool for Generating Armored Redirected T Cells

Published:2021-04-01 Issue:2 Volume:31 Page:145-154
ISSN:2159-3337
Container-title:Nucleic Acid Therapeutics
language:en
Short-container-title:Nucleic Acid Therapeutics

Author:

Ceccarello Erica¹²³,Tabaglio Tommaso¹,Koh Sarene⁴⁵,Oei Vincent²,Teo Winnie¹,Jonathan Owen Julianto¹,Pavesi Andrea¹,Chen Qingfeng¹,Bertoletti Antonio²,Wee Keng Boon¹,Guccione Ernesto¹⁶

Affiliation:

1. Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

2. Duke-NUS Medical School, Singapore, Singapore.

3. IMMUNOA Pte Ltd, Singapore, Singapore.

4. Lion TCR Pte Ltd, Singapore, Singapore.

5. Singapore Immunology Network, Agency for Science and Technology (A*STAR), Singapore, Singapore.

6. Department of Oncological Sciences and Pharmacological Sciences, Center for Therapeutics Discovery, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://www.liebertpub.com/doi/pdf/10.1089/nat.2020.0905

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1. Multispecific anti-HIV duoCAR-T cells display broad in vitro antiviral activity and potent in vivo elimination of HIV-infected cells in a humanized mouse model

2. T Cells Expressing a Chimeric Antigen Receptor That Binds Hepatitis B Virus Envelope Proteins Control Virus Replication in Mice

3. Chimeric antigen receptor (CAR)-engineered T cells redirected against hepatitis C virus (HCV) E2 glycoprotein

4. Lymphocytes transiently expressing virus-specific T cell receptors reduce hepatitis B virus infection

5. Turning the tables on cytomegalovirus: targeting viral Fc receptors by CARs containing mutated CH2–CH3 IgG spacer domains

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