Epitope Mapping of an Anti-Human Epidermal Growth Factor Receptor Monoclonal Antibody (EMab-51) Using the RIEDL Insertion for Epitope Mapping Method-Reference-Cited by-同舟云学术

Epitope Mapping of an Anti-Human Epidermal Growth Factor Receptor Monoclonal Antibody (EMab-51) Using the RIEDL Insertion for Epitope Mapping Method

Published:2021-08-01 Issue:4 Volume:40 Page:149-155
ISSN:2167-9436
Container-title:Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
language:en
Short-container-title:Monoclonal Antibodies in Immunodiagnosis and Immunotherapy

Author:

Nanamiya Ren¹,Sano Masato¹,Asano Teizo¹,Yanaka Miyuki¹,Nakamura Takuro¹,Saito Masaki²,Tanaka Tomohiro¹,Hosono Hideki¹,Tateyama Nami¹,Kaneko Mika K.¹,Kato Yukinari¹²³^ORCID

Affiliation:

1. Department of Antibody Drug Development, Tohoku University Graduate School of Medicine, Sendai, Japan.

2. Department of Molecular Pharmacology, Tohoku University Graduate School of Medicine, Sendai, Japan.

3. New Industry Creation Hatchery Center, Tohoku University, Sendai, Japan.

Publisher

Mary Ann Liebert Inc

Subject

Immunology,Immunology and Allergy

Link

https://www.liebertpub.com/doi/pdf/10.1089/mab.2021.0010

Reference41 articles.

1. Review of epidermal growth factor receptor biology

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3. Two EGF molecules contribute additively to stabilization of the EGFR dimer

4. Stabilization of an active dimeric form of the epidermal growth factor receptor by introduction of an inter-receptor disulfide bond

5. Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation.

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