Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy-Reference-Cited by-同舟云学术

Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy

Published:2018-05-10 Issue:14 Volume:28 Page:1265-1285
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Roos Jessica¹²,Peters Marcus³,Maucher Isabelle V.¹,Kühn Benjamin¹,Fettel Jasmin¹,Hellmuth Nadine²,Brat Camilla²,Sommer Benita¹,Urbschat Anja⁴⁵,Piesche Matthias⁵⁶,Vogel Anja¹⁷,Proschak Ewgenij¹,Blöcher René¹,Buscató Estella¹,Häfner Ann-Kathrin¹,Matrone Carmela⁵,Werz Oliver⁸,Heidler Juliana⁹,Wittig Ilka⁹,Angioni Carlo¹⁰,Geisslinger Gerd⁷¹⁰,Parnham Michael J.⁷,Zacharowski Kai²,Steinhilber Dieter¹,Maier Thorsten J.²⁵

Affiliation:

1. Institute of Pharmaceutical Chemistry, Goethe-University, Frankfurt, Germany.

2. Department for Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt, Germany.

3. Department of Experimental Pneumology, Ruhr University Bochum, Bochum, Germany.

4. Department of Urology and Pediatric Urology, University Hospital Marburg, Philipps-University Marburg, Marburg, Germany.

5. Department of Biomedicine, Aarhus University, Aarhus C, Denmark.

6. Biomedical Research Laboratories, Medicine Faculty, Catholic University of Maule, Talca, Chile.

7. Project Group for Translational Medicine and Pharmacology TMP, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Frankfurt, Germany.

8. Institute of Pharmacy, Department of Pharmaceutical and Medicinal Chemistry, Friedrich Schiller University Jena, Jena, Germany.

9. Department of Functional Proteomics, SFB 815 Core Unit, Faculty of Medicine, Goethe-University, Frankfurt, Germany.

10. Pharmazentrum Frankfurt/ZAFES, Institute of Clinical Pharmacology, Goethe-University, Frankfurt, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/ars.2017.7155

Reference69 articles.

1. Nitroparacetamol exhibits anti-inflammatory and anti-nociceptive activity

2. Electrophilic Fatty Acid Species Inhibit 5-Lipoxygenase and Attenuate Sepsis-Induced Pulmonary Inflammation

3. Cyclooxygenase-independent chemoprevention with an aspirin derivative in a rat model of colonic adenocarcinoma

4. Dimethyl fumarate in the treatment of relapsing–remitting multiple sclerosis: an overview

5. NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols

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