Efficient and Fast Generation of Relevant Disease Mouse Models by In Vitro and In Vivo Gene Editing of Zygotes-Reference-Cited by-同舟云学术

Efficient and Fast Generation of Relevant Disease Mouse Models by In Vitro and In Vivo Gene Editing of Zygotes

Published:2022-06-01 Issue:3 Volume:5 Page:422-434
ISSN:2573-1599
Container-title:The CRISPR Journal
language:en
Short-container-title:The CRISPR Journal

Author:

Sanchez-Baltasar Raquel¹²,Garcia-Torralba Aida³⁴,Nieto-Romero Virginia³⁴,Page Angustias²⁵,Molinos-Vicente Andrea³⁴,López-Manzaneda Sergio⁶⁷⁸,Ojeda-Pérez Isabel³⁴,Ramirez Angel²⁵,Navarro Manuel²⁵,Segovia José Carlos³⁴^ORCID,García-Bravo María³⁴

Affiliation:

1. Molecular and Translational Oncology Division, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain.

2. Instituto de Investigación Sanitaria Hospital 12 de octubre (imas12), Madrid, Spain.

3. Cell Technology Division, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIEMAT/CIBERER), Madrid, Spain.

4. Advanced Therapies Unit, Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), Madrid, Spain.

5. Molecular and Translational Oncology Division, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas and Centro de Investigación Biomédica en Red de Cáncer (CIEMAT/CIBERONC), Madrid, Spain.

6. Epithelial Biomedicine Division, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT), Madrid, Spain.

7. Department of Biomedical Engineering, Carlos III University (UC3M), Madrid, Spain.

8. Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER) U714, Madrid, Spain.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Biotechnology

Link

https://www.liebertpub.com/doi/pdf/10.1089/crispr.2022.0013

Reference35 articles.

1. The mouse ascending: perspectives for human-disease models

2. Using the mouse to model human disease: increasing validity and reproducibility