Bio-Orthogonal Chemistry Conjugation Strategy Facilitates Investigation of N-methyladenosine and Thiouridine Guide RNA Modifications on CRISPR Activity
Author:
Affiliation:
1. Department of Chemistry, University at Albany, SUNY, Albany, New York, USA.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Biotechnology
Link
https://www.liebertpub.com/doi/pdf/10.1089/crispr.2022.0065
Reference58 articles.
1. Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2. Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
3. Genetic Screens in Human Cells Using the CRISPR-Cas9 System
4. Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
5. Harnessing type I CRISPR–Cas systems for genome engineering in human cells
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