Novel and Engineered Type II CRISPR Systems from Uncultivated Microbes with Broad Genome Editing Capability
Author:
Affiliation:
1. Metagenomi, Inc., Discovery, Emeryville, California, USA.
2. Bayer AG, Research & Development, Pharmaceuticals, Leverkusen, Germany.
3. Metagenomi Inc., Pre-clinical, Emeryville, California, USA.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Biotechnology
Link
https://www.liebertpub.com/doi/pdf/10.1089/crispr.2022.0090
Reference51 articles.
1. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
2. Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
3. Type II-C CRISPR-Cas9 Biology, Mechanism, and Application
4. In vivo genome editing using Staphylococcus aureus Cas9
5. In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
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