CRISPR-Cas9-Mediated Intersectional Knockout of Glycogen Synthase Kinase 3β in D2 Receptor–Expressing Medial Prefrontal Cortex Neurons Reveals Contributions to Emotional Regulation-Reference-Cited by-同舟云学术

CRISPR-Cas9-Mediated Intersectional Knockout of Glycogen Synthase Kinase 3β in D2 Receptor–Expressing Medial Prefrontal Cortex Neurons Reveals Contributions to Emotional Regulation

Published:2020-06-01 Issue:3 Volume:3 Page:198-210
ISSN:2573-1599
Container-title:The CRISPR Journal
language:en
Short-container-title:The CRISPR Journal

Author:

Khlghatyan Jivan¹²,Beaulieu Jean-Martin¹

Affiliation:

1. Department of Pharmacology and Toxicology, University of Toronto, Medical Sciences Building, Toronto, Canada

2. Department of Psychiatry and Neuroscience, Faculty of Medicine, Université Laval, Québec-City, Canada.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Biotechnology

Link

https://www.liebertpub.com/doi/pdf/10.1089/crispr.2019.0075

Reference48 articles.

1. Light and Electron Microscopy Study of Glycogen Synthase Kinase-3β in the Mouse Brain

2. Differential Roles of Glycogen Synthase Kinase 3 Subtypes Alpha and Beta in Cortical Development

3. Developmental Inhibition of Gsk3 Rescues Behavioral and Neurophysiological Deficits in a Mouse Model of Schizophrenia Predisposition

4. In Vivo Regulation of Glycogen Synthase Kinase-3β (GSK3β) by Serotonergic Activity in Mouse Brain

5. Loss of neuronal GSK3β reduces dendritic spine stability and attenuates excitatory synaptic transmission via β-catenin

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