1. Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada.
2. Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
3. Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
4. Department of Physiology, University of Toronto, Toronto, Ontario, Canada.
5. Department of Anesthesia, University of Toronto, Toronto, Ontario, Canada.
6. Department of Surgery, University of Toronto, Toronto, Ontario, Canada.