Sniffing for Gene-Silencing Efficiency of siRNAs in HeLa Cells in Comparison with That in HEK293T Cells: Correlation Between Knockdown Efficiency and Sustainability of siRNAs Revealed by FRET-Based Probing-Reference-Cited by-同舟云学术

Sniffing for Gene-Silencing Efficiency of siRNAs in HeLa Cells in Comparison with That in HEK293T Cells: Correlation Between Knockdown Efficiency and Sustainability of siRNAs Revealed by FRET-Based Probing

Published:2013-04 Issue:2 Volume:23 Page:152-159
ISSN:2159-3337
Container-title:Nucleic Acid Therapeutics
language:en
Short-container-title:Nucleic Acid Therapeutics

Author:

Shin Seonmi¹,Kim Yea Seul¹,Kim Jisu¹,Kwon Hyun-Mi²,Kim Dong-Eun²,Hah Sang Soo¹

Affiliation:

1. Department of Chemistry and Research Institute for Basic Sciences, Kyung Hee University, Seoul, South Korea.

2. Department of Bioscience and Biotechnology, Konkuk University, Seoul, South Korea.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/nat.2012.0396

Reference35 articles.

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2. Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA-mediated gene silencing

3. siRNA in human cells selectively localizes to target RNA sites

4. RNA Interference in Mammalian Cells by Chemically-Modified RNA

5. The promises and pitfalls of RNA-interference-based therapeutics

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